David Bainbridge from Cambridge University (BSP 63)

bainbridge-150 Episode 63 of the Brain Science Podcast is an interview with David Bainbridge, author of Teenagers: A Natural History. Our focus is on how the brain changes during the teenage years. Bainbridge teaches vetinary anatomy and reproductive biology at Cambridge University and has published several other popular science books including Beyond the Zonules of Zinn: A Fantastic Journey Through Your Brain, which I discussed back in Episode 32.

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"Did My Neurons Make Me Do It?" with Warren Brown (BSP 62)

W-Brown-150 Episode 62 of the Brain Science Podcast is an interview with Warren Brown, PhD, co-author (with Nancey Murphy) of Did My Neurons Make Me Do It?: Philosophical and Neurobiological Perspectives on Moral Responsibility and Free Will. This book was discussed in detail back in Episode 53, but this interview gave me a chance to discuss some of the book's key ideas with Dr. Brown. We focused on why a non-reductive approach is needed in order to formulate ideas about moral responsibility that are consistent with our current neurobiological understanding of the mind.

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Allen Institute for Brain Research (BSP 61)

Allan Jones, PhD
Allan Jones, PhD
Episode 61 of the Brain Science Podcast is an interview with Allan Jones, PhD, the Chief Science Officer of the Allen Institute for Brain Research in Seattle, Washington. The Allen Institute is a non-profit research organization founded by Paul Allen (co-founder of Microsoft) and is best known for its Mouse Brain Map, which is being used by researchers around the world. The Institute has several other on-going projects including a project to create a map of the human cortex that shows which genes are active in each area. In this interview we discuss both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research. All the maps created by The Allen Institute are freely available on the internet. Dr. Jones also shares his own story and the challenges and rewards of pursuing a career in the non-profit biotech world.

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The Importance of Play (BSP 60)

In Episode 60 of the Brain Science Podcast Ginger Campbell, MD interviews Dr. Stuart Brown, author of Play: How It Shapes the Brain, Opens the Imagination, and Invigorates the Soul. Our focus is on the importance of play for normal mental development and psychological health. We also explore the importance of play in adults.

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Neurophsychologist Chris Frith, PhD (BSP 57)

frith Episode 57 of the Brain Science Podcast is an interview with neuropsychologist Dr. Chris Frith, author of Making up the Mind: How the Brain Creates Our Mental World. Our brain processes information about the world outside us (via our senses) in the same way that it processes information from within our bodies and from our own mental world. In this interview Dr. Frith and I explore the implications from recent discoveries about how our brain generates our mental world.

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Pioneering Neuroscientist Eve Marder, PhD (BSP 56)

evemarder2 Episode 56 of the Brain Science Podcast is an interview with neuroscientist, Eve Marder, PhD. Dr. Marder has spent 35 years studying the somatogastric ganglion of the lobster. In this interview we talk about how she got into neuroscience during its early days, her recent tenure as president of the Society for Neuroscience, and how some of her key discoveries have implications for studying more complex nervous systems.

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Philosopher Patricia Churchland (BSP 55)

bsp-300-hi Episode 55 of the Brain Science Podcast is an interview with highly respected philosopher Patricia Churchland. Churchland is the author of Neurophilosophy and Brain. She is currently on the faculty of the University of California at San Diego and she was a featured speaker at the annual meeting of the Society for Neuroscience in 2008. In this interview we talked about neurophilosophy, which is an approach to philosophy of mind that gives high priority to incorporating the empiric findings of neuroscience. We also talk about the evolving relationship between philosophy and neuroscience. Churchland shares her enthusiasm for how the discoveries of neuroscience are changing the way we see ourselves as human beings. We also talked a little about the issues of reductionism that I first brought up in Episode 53.

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Dr. Michael Merzenich on Brain Plasiticity (BSP 54)

bsp-300-hi Brain Science Podcast #54 is an interview with Dr. Michael Merzenich, one of the pioneers of neuroplasticity. We talk about how the success of the cochlear implant revealed unexpected plasticity in adult brains and about how brain plasticity can be tapped to improve a wide variety of problems including dyslexia, autism, damage from disease and injury. Healthy people of all ages can also tap the resource of brain plasticity to help maintain and improve their mental functions.

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Brain Science Podcast Celebrates its 2nd Anniversary (BSP 52)

gin-bud08-100 Brain Science Podcast #52 is our Second Annual Review Episode. We review some of the highlights from 2008. I also discuss the various other on-line resources that I have created for listeners. Then we look ahead to what I have planned for 2009. This episode is aimed at all listeners, including those who are new to the show.

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Synapse Evolution with Dr. Seth Grant (BSP 51)

Episode 51 of the Brain Science Podcast is an interview with Dr. Seth Grant from Cambridge University, UK.  Dr. Grant's work focuses on the proteins that make up the receptors within synapses. (Synapses are the key structures by which neurons send and receive signals.) By comparing the proteins that are present in the synapses in different species Dr. Grant has come to some surprising conclusions about the evolution of the synapse and the evolution of the brain. (Read more...)

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Dr. Brenda Milner: Pioneer of Memory Research (BSP 49)

Brain Science Podcast #49 is an interview with pioneering neuroscientist, Brenda Milner, PhD. Dr. Milner is known for her contributions to understanding memory and her work with split-brain patients. Her work as an experimental psychologist has been fundamental to the emergence of the field of cognitive neuroscience. This interview is a follow-up of Dr. Milner's recent interview with Dr. Marc Pelletier on Futures in Biotech. I highly recommend listening to both interviews.

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Listen to Dr. Milner on Futures in Biotech (Episode33)

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Our "Big Brain" with Dr. Gary Lynch (BSP 48)

Episode 48 of the Brain Science Podcast is an interview with Gary Lynch, PhD, co-author of Big Brain: The Origins and Future of Human Intelligence. While it is generally agreed that one of the most striking features of the human brain is its large size, not everyone agrees about how and why our brains came to be so large. In this interview Dr. Lynch presents some rather radical theories about how the human brain evolved. We discuss the pros and cons of his theories as well as the challenges faced by researchers trying to work in this field.

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The next episode of the Brain Science Podcast will be an interview with Dr. Brenda Milner. This interview will is a follow-up to Marc Pelletier's excellent interview of Dr. Milner on Futures in Biotech: http://www.twit.tv/fib33.

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Michael Arbib on Mirror Neurons (BSP 39)

Episode 39 of the Brain Science Podcast is an interview with Dr. Michael Arbib from the University of Southern California. Dr. Arbib's work with functional brain imaging has established the presence of mirror neurons in the human brain. In our interview we focused on the role of mirror neurons in imitation and language. In particular I questioned Dr. Arbib about the Mirror System Hypothesis (MSH) of Language Evolution that he proposed in 1998 with Giacomo Rizzolatti. We also explored how this hypothesis diverges from the universal grammar proposed by Noam Chomsky. Dr. Arbib also shared his enthusiasm for future research and we talked about the special challenges caused by the interdisciplinary nature of modern neuroscience.

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Interview with Jeff Hawkins "On Intelligence" (BSP 38)

Jeff Hawkins Episode 38 of the Brain Science Podcast is an interview with Jeff Hawkins, author of On Intelligence. Hawkins is well-known for founding Palm Computing and Handspring. He invented the Grafitti handwriting recognition system and helped develop the Palm Trio SmartPhone. Since he published his bestseller On Intelligence, he has devoted his work to his passion for neuroscience. His current company Numenta is developing software that models the hierarchal structure of the neocortex. In this interview we talk about the ideas in Hawkins book and how he is applying them to develop a computer model of cortical function. This is a follow-up to Episode 2, which first aired in December of 2006.

Listen to Dr. Campbell interview Jeff Hawkins.

Links and References:

Jeff Hawkins: wikipedia entry Vernon Montcastle: pioneer who proposed that all parts of the brain's cortex work the same way.
  • Vernon Mountcastle (1978), "An Organizing Principle for Cerebral Function: The Unit Model and the Distributed System", The Mindful Brain (Gerald M. Edelman and Vernon B. Mountcastle, eds.) Cambridge, MA: MIT Press (Please let me know if you find this paper on-line!)
  • Perceptual Neuroscience: The Cerebral Cortex by Vernon B. Mountcastle. This 1998 is recommended by Jeff Hawkins, especially for those interested in the technical details of cortical function.
Redwood Institute for Theoretical Neuroscience (UC-Berkeley) founded by Jeff Hawkins Numenta: company website includes extensive educational information about hierarchical temporal memory system (HTM). The company's focus is practical implementation of HTM Theory.

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Mirror Neurons (BSP 35)

Mirrors in the Brain Brain Science Podcast #35 is a discussion of Mirrors in the brain: How our minds share actions, emotions, and experience by Giacomo Rizzolatti and Corrado Sinigaglia. Mirror neurons were discovered in Rizzolatti's lab in Parma Italy in the early 1990's and his book is a detailed to discussion of the experimental evidence in both monkeys and humans. Direct single neuron recordings have been made in monkeys. The evidence in humans is indirect since it is based on mainly on neuroimaging studies like PET scans and fMRI scans. Even so mirror neurons appear to be essential to our ability to understand both the actions and emotions of others. Listen Now. In this episode we also explore the evidence that there are other neurons in the motor areas of the brain that have sensory properties and that the areas of the brain traditionally thought to be devoted to sensory functions also contain neurons with motor properties. Another fascinating discovery is the fact that there are neurons that respond not only to somatosensory inputs (such as being touched) but also to visual or auditory inputs from objects within our peri-personal space. For background on these body maps I recommend listening to Episode 21 and Episode 23. If you are new to the Brain Science Podcast you may want to listen to those episodes first because this week's episode is a little more technical than most. I will be exploring the importance of these discoveries in future episodes.

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Links: Giacomo Rizzolatti- University of Parma Mirror neurons (wikipedia entry) Mirror neurons (Scholarpedia entry written by Dr. Rizzolatti)

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Dan Rather Presents Neuroplasticity

Today HDNet™ is reshowing an episode of Dan Rather Reports called "Mind Science." It is an excellent review of neuroplasticity. It includes interviews with several leading scientists in the field. I especially enjoyed seeing Nobel Laureate Eric Kandel talk about his work with memory. (I talked about Kandel's work on the Brain Science Podcast in Episode 3 and Episode 12.) "Mind Science" also features the Dalai Llama and scientist Richard Davidson talking about the evidence that meditation can change the brain. Rather interviews Sharon Begely about her book Train Your Mind, Change Your Brain: How a New Science Reveals Our Extraordinary Potential to Transform Ourselves (which I discussed in detail in Episode 10 of the Brain Science Podcast). Other scientists featured in the episode include Michael Merzenich on improving brain function as we age and Dr. Edward Taub on his revolutionary approach to stroke rehabilitation. (My show notes for Episode 10 include links for all the scientists interviewed by Rather.) It was particulary gratifying to see Dr. Kandel endorse Ed Taub's Constraint-Induced Movement Therapy. Dr. Taub was interviewed in Episode 28 of the Brain Science Podcast. If you don't get HDNet™ you can watch Dan Rather Reports on-line, via podcast or on Facebook. Summary of relevant episodes of the Brain Science Podcast: itunes-chicklet.gif Subscribe via iTunes™ Subscribe in a reader or podcatcher Subscribe to Brain Science Podcast with Dr. Ginger Campbell by Email

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Rachel Herz talks about Smell (BSP 34)

rachelherz.jpgRachel Herz Episode 34 of the Brain Science Podcast is an interview with Rachel Herz author of The Scent of Desire: Discovering Our Enigmatic Sense of Smell (2007). Dr. Herz teaches at Brown University and she is a leading authority on the psychology of smell. We talk about the how smell works, its role in emotion and memory, why it is so vulnerable, and why smell is much more important than most of us realize. We also consider some of the questions that remain unanswered. Listen to the Rachel Herz interview now. (Right click to download.) Links and References: Rachel Herz The 2004 Nobel Prize for Medicine and Physiology was awarded to Richard Axel and Linda B. Buck for their discoveries of "odorant receptors and the organization of the olfactory system." BuckL, Axel R "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition." Cell. 1991 Apr 5;65(1):175-87. "The (Shocked) Nose Knows" by Gisela Telis ScienceNOW Daily News 27 March 2008 scentofdesire.jpgThe Scent of Desire: Discovering Our Enigmatic Sense of Smell (2007) by Rachel Herz Listen to Episode 34 (Right click to download) Share your comments on the Discussion Forum Audience Survey itunes-chicklet.gif Subscribe via iTunes™ Subscribe in a reader or podcatcher Subscribe to Brain Science Podcast with Dr. Ginger Campbell by Email Donations and Subscriptions are appreciated

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