Synapse Evolution with Dr. Seth Grant (BSP 51)

Episode 51 of the Brain Science Podcast is an interview with Dr. Seth Grant from Cambridge University, UK.  Dr. Grant's work focuses on the proteins that make up the receptors within synapses. (Synapses are the key structures by which neurons send and receive signals.) By comparing the proteins that are present in the synapses in different species Dr. Grant has come to some surprising conclusions about the evolution of the synapse and the evolution of the brain. (Read more...)

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Dr. Brenda Milner: Pioneer of Memory Research (BSP 49)

Brain Science Podcast #49 is an interview with pioneering neuroscientist, Brenda Milner, PhD. Dr. Milner is known for her contributions to understanding memory and her work with split-brain patients. Her work as an experimental psychologist has been fundamental to the emergence of the field of cognitive neuroscience. This interview is a follow-up of Dr. Milner's recent interview with Dr. Marc Pelletier on Futures in Biotech. I highly recommend listening to both interviews.

Listen to Episode 49 of the Brain Science Podcast

Listen to Dr. Milner on Futures in Biotech (Episode33)

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Interview with Nobel Physicist Frank Wilczek (B&I 23)

Episode 23 of Books and Ideas is an interview with Frank Wilczek, PhD from MIT. Dr. Wilczek won the Nobel Prize for Physics in 2004 and recently published an excellent book aimed at general readers: Lightness of Being: Mass, Ether, and the Unification of Forces. This book provides an excellent review of current ideas about the meaning of both matter and space. In his interview Dr. Wilczek helps us understand the current evidence that matter is actually made of particles that are massless. He says "I jokingly say that the more important law is Einstein's Second Law m=E/c² (which is of course just a rearrangement of E=mc²) but this suggests that what we really should be doing is not explaining energy in terms of mass, but explaining mass in terms of energy." The second surprisingly concept that Dr. Wilczek helps us tackle in this interview is the idea that space is not empty. "Space is a medium with a variety of properties that make it, not only an important component of reality, but really the primary component of reality." These ideas are supported by experimental evidence, but the Large Hadron Collider (LHC) near Geneva, Switzerland is expected to expand knowledge even further. The purpose of the LHC is a main focus of this interview. Dr. Wilczek has agreed to come back on Books and Ideas to answer questions about dark matter and string theory.

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Additional Show Notes and Links: Frank Wilczek, PhD Other podcasts mentioned in this episode Recommended Reading: Announcements:

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Our "Big Brain" with Dr. Gary Lynch (BSP 48)

Episode 48 of the Brain Science Podcast is an interview with Gary Lynch, PhD, co-author of Big Brain: The Origins and Future of Human Intelligence. While it is generally agreed that one of the most striking features of the human brain is its large size, not everyone agrees about how and why our brains came to be so large. In this interview Dr. Lynch presents some rather radical theories about how the human brain evolved. We discuss the pros and cons of his theories as well as the challenges faced by researchers trying to work in this field.

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Visit the Brain Science Podcast website for detailed Show Notes and Links.

The next episode of the Brain Science Podcast will be an interview with Dr. Brenda Milner. This interview will is a follow-up to Marc Pelletier's excellent interview of Dr. Milner on Futures in Biotech: http://www.twit.tv/fib33.

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Highlights from Dragon*Con 2008 (B&I 22)

"The Mayor"Ginger as "The Mayor" (see below) Episode 22 of Books and Ideas is my summary of my recent trip to Dragon*Con 2008 in Atlanta, Georgia. It was a great opportunity to spend time with other podcasters, but the highlight of the weekend was our late night performances of Dr. Horrible's Sing-Along Blog. I had a non-singing part in Act 3 (as the mayor).

Listen to Episode 22 of Books and Ideas

Show Notes and Links

Stuff I did:

Podcasters:

Podcasting Awards As I mentioned above I really enjoyed being a part of the first live performances of Joss Whedon's Dr. Horrible's Sing-Along Blog (think Rocky Horror Picture Show) which was put on by the cast and crew of Buffy Between the Lines. Writer Tabitha Grace Smith was interviewed in Episode 18 of Books and Ideas. Kinsey, who made a video of my brief appearance does a very interesting podcast about living in Brazil (called Brazilianisms). Go to http://buffybetweenthelines.com to learn more about the rest of the cast. Special thanks to Beatnik Turtle for the new theme song "The Open Door."

Listen to Episode 22 of Books and Ideas

Subscribe to Books and Ideas Podcast Subscribe to Books and Ideas in iTunes™ Subscribe Books and Ideas Podcast by email Leave comments at the Discussion Forum If I met you at Dragon*Con but forgot to link to your site please send me email at docartemis at gmail.com!
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Recorded LIVE at Dragon*Con 2008 (BSP 46)

Dragon*Con 2008 Dragon*Con 2008 Brain Science Podcast #46 is a discussion of brain imaging with Dr. Shella Keilholz and Dr. Jason Schneiderman. The focus of our discussion is functional magnetic resonance imaging (fMRI), which is revolutionizing neuroscience. We talked about both the strengths and weaknesses of this technique. Both of my guests agree that mainstream coverage of this technique tends to exagerate what we can actually tell from this kind of brain scan. An important principle is that the scan of any single individual can vary greatly from day-to-day, which means that valid conclusions require data from a large number of people.

Listen to Episode 46 of the Brain Science Podcast

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Send email feedback to Ginger Campbell, MD at docartemis at gmail.com

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Attention Deficit Disorder with Dr. John Ratey (BSP 45)

Have you ever wondered why a child with ADD can play videos games for hours but can’t concentrate on his homework for a few minutes? This is one of the paradoxes of attention-deficit disorder that  John J Ratey, MD, co-author of Driven To Distraction : Recognizing and Coping with Attention Deficit Disorder from Childhood Through Adulthood, explains in Episode 45 of the Brain Science Podcast. During this interview Dr. Ratey discusses the latest findings about the biological basis of what he calls “attention variability disorder.” He also offers practical advice for patients and parents dealing with ADD/ADHD. One very important, and somewhat surprising, fact that he shares is that patients who are treated with medications during adolescence have a significantly lower risk of developing problems with addiction and drug abuse later on compared to those who are not treated. Also, successful “ADDers” like Michael Phelps show that “having a mission” makes a huge difference. Dr. Ratey’s most recent book is Spark: The Revolutionary New Science of Exercise and the Brain, which he discussed with me (Dr. Campbell) in Episode 33.

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Links and Show Notes for Episode 45

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Daniel Siegel, MD on Meditation and the Brain (BSP 44)

Daniel Siegel, MD In Episode 44 of the Brain Science Podcast I talk with Daniel Siegel, MD about meditation and the brain. Dr. Siegel is the author of several books including The Mindful Brain: Reflection and Attunement in the Cultivation of Well-Being. In this interview we review the scientific evidence about how mindfulness meditation changes the brain, both in terms of short term activity and in terms of long-term structural changes. The evidence is convincing that a regular mindfulness practice can be an important element of brain health.

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Part 2 of "On Being Certain" with Robert Burton, MD (BSP 43)

Episode 43 of the Brain Science Podcast is an interview with Robert A Burton, MD, author of On Being Certain: Believing You Are Right Even When You're Not, which I discussed in Episode 42. Dr. Burton tells us what inspired him to write this book and we explore some of the implications of the fact that what he calls the "feeling of knowing" comes from our unconscious, including the fact that it is not as reliable as it feels.

Listen to Episode 43 of the Brain Science Podcast

Show Notes and Links

Robert A Burton, MD

Previous Episodes of the Brain Science Podcast:
  • Episode 42: Part 1 of our discussion of On Being Certain
  • Episode 13: Unconscious Decisions-featuring Blink by Malcom Gladwell
  • Episode 15: Interview with Read Montague about unconscious decisions
Other scientists/writers mentioned in this episode: Other terms mentioned in the interview: Cotard's Syndrome: when the patient believes they do not exist or that they are dead cognitive dissonance: a mismatch between what one believes and what the evidence supports

Listen to Episode 43 of the Brain Science Podcast

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Review: "On Being Certain" (BSP 42)

Episode 42 of the Brain Science Podcast is a discussion of On Being Certain: Believing You Are Right Even When You're Not by Robert Burton, MD. This part 1 of a two part discussion of the unconscious origins of what Dr. Burton calls "the feeling of knowing." In Episode 43 I will interview Dr. Burton. Today's episode provides an overview of Dr. Burton's key ideas. In past episodes I have discussed the role of unconscious decision-making. On Being Certain: Believing You Are Right Even When You're Not by Robert Burton, MD takes this topic to a new level. First, Dr. Burton discusses the evidence that the "feeling of knowing" arises from parts of our brain that we can neither access or control. Then he discusses the implications of this finding, including the fact that it challenges long-held assumptions about the possibility of purely rational thought.

Listen to Episode 42 of the Brain Science Podcast

References and Links:

On Being Certain: Believing You Are Right Even When You're Not by Robert Burton, MD

Neisser, U., and Harsh, N. "Phantom Flashbulbs: False Recollections of Hearing the News about Challenger,"  in Affect and Accuracy in Recall: Studies of "Flashbulb" Memories, Winograd, E., and Neisser, U., (New York: Cambridge University Press, 1992)

The Seven Sins of Memory: How the Mind Forgets and Remembers by Daniel L. Schacter

The Feeling of What Happens: Body and Emotion in the Making of Consciousness by Antonio Damasio

Philosophy in the Flesh : The Embodied Mind and Its Challenge to Western Thought by George Lakoff and Mark Johnson

Other Scientists Mentioned in this Episode:

  • Leon Festinger-proposed the theory of cognitive dissonance in 1957
  • Joseph Ledoux-research with rats and the role of the amygdala in the fear response
  • Michael Merzenich-showed how the auditory cortex in young rats is affected by experience

Listen to Episode 42 of the Brain Science Podcast

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Interview with Linguist Alice Gaby (BSP 41)

Episode 41 of the Brain Science Podcast is an interview with Alice Gaby, PhD, from the University of California-Berkeley. Dr. Gaby is a linguist who studies the role of language in cognition as well as the aboriginal languages of Australia. In this episode Dr. Gaby introduces some of the basic areas of linguistics. We also talk about why linguistics is important to understanding brain function, as well as the importance of interdisciplinary communication to advancement in both fields. Dr. Gaby's infectious enthusiasm makes this potentially intimidating subject accessible to everyone.

Listen to Episode 41 of the Brain Science Podcast

Visit the Brain Science Podcast website for more information, including detailed show notes and links.

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Dr. Eugenie Scott on Teaching Evolution (B&I 21)

Eugenie Scott, the Executive Director of the National Center for Science Education, was interviewed in Episode 21 of Books and Ideas. The focus of our conversation was the importance of teaching evolution in the public schools. Dr. Scott and the NCSE have worked for over 20 years to promote the teaching of evolution because it is an essential component of a modern education in the life sciences. Unfortunately, nearly 150 years after Darwin's On the Origin of Species (1859) many Americans still reject this fundamental idea and much of Scott's work is focused on trying to keep creationism and so-called Intelligent Design out of school curriculum. Recently the NCSE launched a very valuable site called Expelled Exposed, which focuses on exposing the many inaccuracies presented in Ben Stein's recent pro-intelligent design "documentary" Expelled. One of the things that has come out in numerous interviews is that the producers of the film mislead all the pro-evolution guests that appear in the film. We discuss this briefly near the end of the interview, but it was not the focus of our discussion. (see below for more links regarding Expelled) Since Dr. Scott has been interviewed about Expelled and Expelled Exposed on several other podcasts, I wanted to focus our interview more on the importance of accurate science education. Also, we discussed the fact that despite the claims of right-wing fundamentalists there are many Christians and people of other faiths who accept the theory of evolution as scientifically valid. Accepting evolution does not mean one is choosing atheism. I think this is a very important distinction because while atheists are outspoken in their support of evolution they represent a small minority. I was encouraged to learn from Dr. Scott that the NCSE is working closely with religious leaders and scientists of faith to try to educate their members. Since Books and Ideas reaches an international audience I thought that it was important that we discuss the origins of the evolution versus creationism controversy, which is unique to the United States. Scott does an excellent job of explaining how our unique religious heritage along with our locally controlled school systems combine to create a situation that most of the world find's rather mystifying. Her book Evolution vs. Creationism: An Introduction also provides an excellent overview of the subject from both an historical and scientific prospective. Finally, we talk about the importance of evolution as a basic idea in modern biology. While we didn't dwell on this, I think we are both concerned about the implications for the future if a majority of young Americans are reaching college without a solid foundation in the principles of evolution. We also talked about why intelligent design fails to meet the basic definition of a scientific theory since it provides no testable hypotheses. Dr. Scott also provides a excellent review of the basic writings for those who want to learn more.

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Links and References: Other Books mentioned by Dr. Scott:
  • Of Pandas and People: The Central Question of Biological Origins by Percival Davis and Dean H. Kenyon : the 1989 textbook that introduced the term “intelligent design”
  • Darwin on Trial by Phillip E. Johnson, 1991.
  • Darwin’s Black Box: The Biochemical Challenge to Evolution by Michael J. Behe
  • The Design Inference: Eliminating Chance through Small Probabilities by William A. Dembski
  • Behe MJ, Snoke DW. 2004. Simulating evolution by gene duplication of protein features that require multiple amino acid residues. Protein Science 10:2651-64.
Responses to Expelled Exposed by Christians

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Third Semi-annual Review Episode (BSP 40)

Episode 40 of the Brain Science Podcast is a look back at the highlights from the last six months. We have talked about numerous topics including brain plasticity, mirror neurons, language, brain rhythms, and the sense of smell. We talked with 9 guests and we have also explored the practical implications of neuroscience, including the importance of sleep and exercise to brain health. This brief review episode is intended for both new listeners and long-time subscribers.

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For detailed show notes including links to all the resources discussed in the episode

please visit the Brain Science Podcast website

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Michael Arbib on Mirror Neurons (BSP 39)

Episode 39 of the Brain Science Podcast is an interview with Dr. Michael Arbib from the University of Southern California. Dr. Arbib's work with functional brain imaging has established the presence of mirror neurons in the human brain. In our interview we focused on the role of mirror neurons in imitation and language. In particular I questioned Dr. Arbib about the Mirror System Hypothesis (MSH) of Language Evolution that he proposed in 1998 with Giacomo Rizzolatti. We also explored how this hypothesis diverges from the universal grammar proposed by Noam Chomsky. Dr. Arbib also shared his enthusiasm for future research and we talked about the special challenges caused by the interdisciplinary nature of modern neuroscience.

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Related Episodes:

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Mindfulness Meditation with Delany Dean (B&I 20)

Delany DeanEpisode 20 of Books and Ideas is an interview with forensic psychologist Delany Dean, PhD. Dr. Dean began her career as a criminal lawyer but his interest in the mind and the brain lead her to a second career as a clinical psychologist. Besides forensic psyschology she has extensive experience with therapies based on the use of mindfulness meditation. In this interview, Dr. Campbell and Dr. Dean share there personal experiences with meditation, and Dr. Dean explains why she feels mindfulness meditation provides a extremely valuable tool for helping people deal with a wide range of problems, including the stress that we all face from time to time. They also give practical advise for listeners interested in beginning a mindfulness practice.

Listen to Delany Dean's Interview.

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Links and References:

Mind Expressions: Delany's Dean's blog Teachers and Scientists mentioned in the interview: Books and Other Resources for Beginners: You can find more references at the Brain Science Podcast Discussion Forum where there is on-going thread devoted to meditation and the Brain. There is also a section for discussing episodes of Books and Ideas.

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"Brain Rules" with Dr. John Medina (BSP 37)

John Medina, PhD Episode 37 of the Brain Science Podcast is an interview with Dr. John Medina, author of Brain Rules: 12 Principles for Surviving and Thriving at Work, Home, and School. We talk about how exercise, sleep, and stress effect our brains with an emphasis on practical advice for healthier brain function. We also look at how research on memory, vision and the brain's attention system suggests how we can improve our ability to learn and our ability to share ideas with others. Dr. Medina's focus is on considering real world examples of how our schools and work environments could be reformed to utilize the growing knowledge of neuroscience. But he also stresses the importance of compiling sufficient experimental data before embarking on new programs.

Listen to Episode 37 now (left click to listen, right click to download mp3).

Links and References: Brain Rules: 12 Principles for Surviving and Thriving at Work, Home, and School (Book & DVD) by John Medina The book's website contain extensive references and instructive videos. YouTube Video of John Medina speaking at Google™.

Listen to Brain Science Podcast #37

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Art Glenberg discusses Embodied Cognition (BSP 36)

Art Glenberg, PhD Episode 36 of the Brain Science Podcast is an interview with Arthur Glenberg, PhD about embodied cognition. Dr. Glenberg recently moved to Arizona State University after over 30 years at the University of Wisconsin's Laboratory of Embodied Cognition. His research focuses on the relationship between embodiment and language. In this interview we explore the experimental evidence for a theory of language that embraces the concept that our language abilities are actually rooted in our perceptual and motor abilities. Dr. Glenberg also explains how his work has practical implications in helping children learn how to read. Since Dr. Glenberg has had a long career as a working research scientist, this interview also provided an opportunity to explore how scientific hypotheses are formed and how experiments are designed to test these hypothesis. I think this interview will give you a fascinating look into the real world of cognitive psychology.

Listen to Dr. Glenberg's Interview (left click to listen, right click to download)

Links and References: Arthur Glenberg, PhD Other Scientists Mentioned in the Episode:
  • George Lakoff: pioneering linguist
  • James Gibson-known for his ideas about affordances
  • William Epstein-emeritus professor at the University of Wisconsin
  • Joseph Campos: University of California (Berkelely)
  • Amy Needham and Amanda Woodard-experiments with velcro mits and infant cognition
  • David A Havas: graduate student and co-author with Dr. Glenberg
  • Mike Kashak: Florida State University
  • Mike Rinck: German co-author-see paper under Glenberg (more papers)
  • Vittorio Gallese, Dept of Neuroscience, University of Parma, Italy (where mirror neurons were discovered): extensive experimental with motor neurons in monkeys
  • Fritz Stack (Germany): experiments showing that facial experiments affect mood and cognition
References: Listen to Dr. Glenberg's Interview (left click to listen, right click to download)

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